A new review argues that policy and stigma, rather than lack of ECS science, are now the main barriers to cannabinoid medicine. I agree, but an important gap remains: medicine still lacks a practical clinical physiology of the endocannabinoid system.
Tag: ECS physiology
Announcements
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Open letter to CB1 researchers
An open letter inviting researchers to investigate whether metabolic state influences CB1 receptor stability, trafficking and degradation across insulin-sensitive tissues, and whether this represents a broader principle of endocannabinoid system regulation.
Commentary
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The missing membrane layer in a new marathon endocannabinoid study
A new BMC Medicine study shows that marathon running triggers distinct temporal changes in anandamide, 2-AG and arachidonic acid. The missing piece may be the runners’ membrane fatty-acid state before exercise.
Commentary
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The Enzyme Inhibitor Paradox: Why Anti-Obesity Drugs Keep Failing
A new study just proved something remarkable: researchers found a way to slash insulin levels by 53% in just two hours. Food intake dropped 23%. Body weight fell within 24 hours. The pharmaceutical industry should be celebrating. Except there’s a problem. By day seven, it stopped working. Completely. The mice…