Tag: physiology

Infographic slide breaking down the Endocannabinoid System (ECS) as a dietary precursor-driven symbiotic homeostatic suprasystem, with sequential symbols: a fork and knife for 'dietary' (fueled by food nutrients), a building block for 'precursor-driven' (built from fatty acids), reciprocal arrows with gut microbes for 'symbiotic' (mutual interaction with microbiome), a yin-yang for 'homeostatic' (maintains internal balance), and a network diagram for 'suprasystem' (integrates multiple organ systems)

The Endocannabinoid System: Dietary Precursor-Driven ECS & Medical Education Gap

Posted on July 23, 2025 By Stefan Broselid

The Misunderstood Master Regulator The endocannabinoid system (ECS) is often considered the “cannabis system,” but this label ignores its true—and far broader and more important—role in holistic health. Instead of being defined by external substances, the ECS is a dietary precursor-driven, symbiotic, homeostatic suprasystem: a dynamic physiological network that maintains body-wide…

Endocannabinoid System (ECS)

Illustration of an overweight person sitting next to a stylized neuron and molecular structures, visually representing the concept that obesity rewires the endocannabinoid system.

Obesity Rewires Your Endocannabinoid System (ECS): How Fat, Liver, Heart & Brain Are Transformed

Posted on June 17, 2025 By Stefan Broselid

Obesity is more than excess fat—it’s a disorder of endocannabinoid system (ECS) dysfunction. Explore how obesity rewires CB1 signaling in fat, liver, heart, and brain, driving chronic disease.

Scientific Summary

Dietary Omega-3/6 Balance: New Research Links Fatty Acid Ratios to Chronic Disease and Longevity

Posted on March 12, 2025March 12, 2025 By Stefan Broselid

New research reveals countries with high omega-3 consumption enjoy 2.63 extra years of healthy life expectancy compared to nations with typical Western diets. Groundbreaking clinical evidence shows omega-6 fatty acids increase inflammatory markers while omega-3s counteract these effects. Your starting omega-3/6 baseline significantly impacts how your body responds to dietary interventions, offering new insights for personalized nutrition approaches.

Critical analysis

The Hidden Epidemic: ECS Dysfunction at the Crossroads of Autism and Obesity

Posted on February 28, 2025March 4, 2025 By Stefan Broselid

Explore how modern diets rich in omega-6 fatty acids may disrupt the endocannabinoid system (ECS), linking autism spectrum disorder (ASD) and metabolic syndrome through shared mechanisms of inflammation, neurodevelopment, and metabolism.

The Missing Link in Medicine: How the Endocannabinoid System (ECS) could Revolutionize Healthcare

Posted on February 1, 2025February 1, 2025 By Stefan Broselid

Why isn’t the endocannabinoid system (ECS) taught in medical schools? This ancient system regulates hunger, pain, metabolism, and immunity—and it’s under attack from processed foods and outdated education. Learn how omega-6 fats disrupt the ECS, drive chronic disease, and what we can do to fix healthcare. Share this video to…

Commentary

Challenging the Daily Mail: The Science Behind Medical Cannabis for ADHD and Menopause

Posted on January 27, 2025January 27, 2025 By Stefan Broselid

Professor Sir Robin Murray’s claim that ‘cannabis has the same effect as drinking a pint’ for psychological conditions, published in the Daily Mail, oversimplifies the science behind medical cannabis. This commentary explores the evidence supporting cannabis as a therapeutic option for ADHD and menopause while addressing misconceptions about its efficacy and safety.

Educational video

Understanding Medical Cannabis and the ECS

Posted on December 13, 2024December 13, 2024 By Stefan Broselid

The endocannabinoid system (ECS) is one of the most important physiological systems in our body, regulating processes like mood, sleep, and pain. Yet, many healthcare professionals know little about it. This disconnect becomes even more striking when paired with the high but till growing acceptance of medical cannabis as a…

Critical analysis

Illustration showing integration points of ECS knowledge into medical curricula, featuring a medical educator presenting a flowchart of physiological systems and their connections to the Endocannabinoid System.

Beyond Omission: Integrating ECS into Medical Education – A Blueprint for Change

Posted on November 26, 2024November 26, 2024 By Stefan Broselid

Executive Summary An analysis of the Physiological Society’s 2020 “Physiological Objectives for Medical Students” curriculum guide reveals a critical gap: the complete omission of the Endocannabinoid System (ECS). This official curriculum guidance document, which establishes core physiological knowledge for new doctors, overlooks a system fundamental to maintaining homeostasis across multiple…

Scientific Summary

The Great Medical Education Blind Spot: How 2,470 ECS Publications Go Ignored

Posted on November 24, 2024November 24, 2024 By Stefan Broselid

A critical analysis of four influential publications reveals a troubling disconnect in medical education: while thousands of researchers document the Endocannabinoid System’s crucial role in homeostatic regulation, mainstream medical education continues to operate in isolation from this knowledge. This systematic exclusion creates dangerous knowledge gaps in healthcare delivery.

Scientific Summary

"Diagram showing parallel metabolic pathways of omega-3 and omega-6 PUFAs, illustrating the dramatic increase in LA consumption from 1% to 8% between 1900-2000, and its downstream effects on endocannabinoid signaling and metabolic health.

Beyond Calories: How Dietary Fats Shape Our Cellular Architecture and Determine our Health

Posted on November 19, 2024November 19, 2024 By Stefan Broselid

Nearly two decades ago, researchers warned about the metabolic consequences of high linoleic acid consumption. This post explores how dietary fats shape our cellular architecture through endocannabinoid signaling, and why these warnings remain critically relevant today.