Tag: Obesity

Divided illustration contrasting mainstream omega-6 fatty acid research on left with neglected endocannabinoid system CB1 CB2 receptor pathways anandamide 2-AG hidden behind broken wall on right alongside cannabis leaf and ignored research files

The Missing System: How a Major 2026 Review on Cardiometabolic Health Ignores the Endocannabinoid System

Posted on February 2, 2026February 2, 2026 By Stefan Broselid

Last August, I wrote about a troubling pattern in inflammation research: brilliant scientists studying arachidonic acid metabolism while remaining “blissfully unaware that half the arachidonic acid story exists in a parallel research universe.” I documented how eicosanoid researchers and endocannabinoid scientists study the same substrate, same concentration ranges, same tissues—yet publish in…

Endocannabinoid System (ECS)

Illustration of an overweight person sitting next to a stylized neuron and molecular structures, visually representing the concept that obesity rewires the endocannabinoid system.

Obesity Rewires Your Endocannabinoid System (ECS): How Fat, Liver, Heart & Brain Are Transformed

Posted on June 17, 2025 By Stefan Broselid

Obesity is more than excess fat—it’s a disorder of endocannabinoid system (ECS) dysfunction. Explore how obesity rewires CB1 signaling in fat, liver, heart, and brain, driving chronic disease.

Scientific Summary

The Omega-6/Omega-3 Imbalance: A Hidden Link Between Autism and Obesity?

Posted on July 25, 2024July 29, 2024 By Stefan Broselid

Recent research suggests a surprising connection between the dramatic rise in autism spectrum disorder (ASD) prevalence and obesity rates over the past 50 years. The common thread? A significant shift in our dietary omega-6/omega-3 fatty acid ratio and its effects on the endocannabinoid system. This post examines the compelling evidence and potential implications for public health.