Obesity is more than excess fat—it’s a disorder of endocannabinoid system (ECS) dysfunction. Explore how obesity rewires CB1 signaling in fat, liver, heart, and brain, driving chronic disease.
Tag: CB1 Receptor
Endocannabinoid System (ECS)
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Paracetamol Confirmed as a Direct Analgesic DAGL Inhibitor: New Preprint Evidence
Important Note: This blog post discusses findings from a recent scientific preprint, meaning the research has not yet been formally peer-reviewed. Preprints allow for rapid dissemination of findings, but results should be interpreted cautiously until confirmed by peer-reviewed publication. Recently, we reported on a surprising new way that paracetamol (also known…
Endocannabinoid System (ECS)
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The Agmatine-ECS-ASD Connection: New Hope for ASD by Boosting 2-AG and Calming the Brain
Explore groundbreaking research on agmatine’s connection to the endocannabinoid system (ECS) in Autism (ASD). Discover how it may boost 2-AG, calm brain inflammation, and offer new hope for understanding and potentially supporting ASD.
Commentary
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Seeing is Believing: New Tech Reveals How The Endocannabinoid System Works in Real-Time
A paradigm-shifting review in Neuron (Malhotra et al., 2025) highlights how new technologies allow scientists to visualize endocannabinoid (ECS) dynamics in real-time in behaving animals. This post breaks down the key breakthroughs, including the central role of 2-AG in rapid signaling, its precision, its function in memory and seizures, and the implications for healthcare professionals and medical cannabis.