Commentary Two-panel faculty meeting scene; left, a male professor in a white coat asks ‘Shouldn’t we teach the ECS? I know it’s about a lot more than cannabis’; right, a sweating administrator looks anxious and repeats ‘Shouldn’t we teach the ECS…’; bottom banner reads ‘Let’s start asking the uncomfortable questions!’ with the ECS.education logo and ‘Join the movement!’

Let’s Start Asking the Uncomfortable Questions about the ECS

Posted on By Stefan Broselid

A half-century of medical curricula has overlooked one of human physiology’s master regulators—the endocannabinoid system (ECS). But the conversation is shifting. In faculty rooms across the world, one question is changing the temperature: “Shouldn’t we teach the ECS?” Educational omissions translate directly into gaps in patient care. Closing both is imperative. Every revolution…

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Announcements Illustration announcing “Peer‑review passed” for a publication in the journal “I JCMCS: International Journal of Clinical & Medical Case Studies,” with a facing page reading “Bridging the gap: Integrating the endocannabinoid system into medical education” beside cartoon figures of a lab‑coated clinician holding a clipboard and a person at a laptop, green molecular icons and a cannabis leaf in the background, and a footer line stating “The ECS.education community has a milestone to celebrate.”

From Preprint to Peer Review: ECS.education Paper Accepted in IJCMCS

Posted on By Stefan Broselid

The ECS.education community has a milestone to celebrate: our manuscript, “Bridging the gap: Integrating the endocannabinoid system into medical education,” has passed independent, double‑blind peer review and is now published in the International Journal of Clinical & Medical Case Studies (IJCMCS). Built around three cornerstone ECS.education analyses, the paper consolidates…

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Commentary llustration showing rows of scientists in lab coats and blindfolds standing in a tunnel filled with laboratory equipment, mathematical formulas, and the words “fatty acids” and “anti-inflammatory” written on the walls. Light shines at the end of the tunnel, symbolizing limited vision or awareness. On the right, the text reads “How inflammation research ignores the endocannabinoid system (ECS): When scientific tunnel vision becomes institutional blindness.” The ECS.education logo appears at the bottom right.

How Scientific Tunnel Vision in Inflammation Research Ignores the Endocannabinoid System (ECS)

Posted on By Stefan Broselid

When scientific tunnel vision becomes institutional blindness Lessons from history’s scientific blind spots Science has a troubling habit of missing the forest for the trees. For decades, gastroenterologists dismissed the idea that bacteria could cause stomach ulcers—until Barry Marshall proved Helicobacter pylori was the culprit by infecting himself. Geologists ridiculed…

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Endocannabinoid System (ECS) Illustration showing the link between obesity and dysfunction in the endocannabinoid system (ECS). The image includes a silhouette of an overweight person, a fingerprint, a brain with a cannabis leaf symbol, and a chemical structure with the text 'ECS.education'

Obesity’s metabolic fingerprint is characterised by ECS Dysfunction!

Posted on By Stefan Broselid

Obesity isn’t just about extra weight—it imprints a unique metabolic fingerprint deep within your body. New research reveals that this signature is marked by endocannabinoid system (ECS) dysfunction, driven by dietary fat balance and energy surplus. Learn how what you eat tunes your ECS, shapes your health risks, and why fixing the “input side” of nutrition could help fade the metabolic fingerprint of obesity.

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Critical analysis Illustration depicting a mother breastfeeding her infant, surrounded by icons of BMI, omega-3 and omega-6 fatty acids, a fish, green leaves, and a brain diagram, with the caption 'Maternal Obesity Disrupts Breast Milk PUFA Balance' from ECS.education

Maternal Obesity Disrupts Breast Milk PUFA Balance: New Insights into ECS Programming for Infants

Posted on By Stefan Broselid

Let’s dive right in. In my earlier posts on ECS.education, we’ve talked about how maternal adiposity shapes breast milk’s endocannabinoid system (ECS) and influences infant health. The May 23 piece on ‘The Adiposity Filter: How Maternal Body Fat Reshapes Milk PUFAs for Your Baby’s ECS‘ highlighted shifts in endocannabinoid profiles…

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Endocannabinoid System (ECS) Infographic slide breaking down the Endocannabinoid System (ECS) as a dietary precursor-driven symbiotic homeostatic suprasystem, with sequential symbols: a fork and knife for 'dietary' (fueled by food nutrients), a building block for 'precursor-driven' (built from fatty acids), reciprocal arrows with gut microbes for 'symbiotic' (mutual interaction with microbiome), a yin-yang for 'homeostatic' (maintains internal balance), and a network diagram for 'suprasystem' (integrates multiple organ systems)

The Endocannabinoid System: Dietary Precursor-Driven ECS & Medical Education Gap

Posted on By Stefan Broselid

The Misunderstood Master Regulator The endocannabinoid system (ECS) is often considered the “cannabis system,” but this label ignores its true—and far broader and more important—role in holistic health. Instead of being defined by external substances, the ECS is a dietary precursor-driven, symbiotic, homeostatic suprasystem: a dynamic physiological network that maintains body-wide…

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Commentary Split-screen illustration showing cannabis as a small spark near a heart icon, symbolizing media hype on minor ECS changes and cardiac risks, contrasted with diet as a large bonfire fueled by junk food, representing precursor-driven ECS overdrive and chronic heart inflammation.

Beyond the Buzz: Cannabis Heart Risks vs. Diet-Driven ECS Overload

Posted on By Stefan Broselid

Introduction: Beyond the Buzz – A Flawed Focus on Cannabis Recent headlines have lit up with warnings about cannabis and heart health, fueled by a systematic review showing links to increased risks of strokes, heart attacks, and cardiovascular death. It’s easy to get caught up in the alarm. After all, who doesn’t want to protect their ticker? But here’s where our reasoning goes off track:…

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Uncategorized Illustration summarizing the updated understanding of endogenous 2-AG signaling, highlighting direct interactions with key cellular proteins.

An Update on Endogenous 2-AG Signaling: New Mechanisms and Cellular Integration

Posted on By Stefan Broselid

Introduction: The Evolution of an Idea When I first began my career in molecular pharmacology, the endocannabinoid system (ECS) quickly became a source of intrigue. Here was a unique receptor system, defined by its enigmatic lipid messengers and central role in brain physiology. Like many, I was trained to see 2-arachidonoylglycerol (2-AG) as a classic retrograde messenger, acting through G protein-coupled receptors (GPCRs), and to view intracellular signaling as a tightly…

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