Tag: Metabolic regulation

Scientific illustration showing a CB1 receptor in the cell membrane, with metabolic state influencing receptor stability and lysosomal degradation. Dietary fat composition and carbohydrate-driven insulin responses are shown as upstream factors, with liver, adipose tissue, skeletal muscle, brain, and heart representing insulin-sensitive tissues.

Open letter to CB1 researchers

Posted on September 3, 2026September 3, 2026 By Stefan Broselid

An open letter inviting researchers to investigate whether metabolic state influences CB1 receptor stability, trafficking and degradation across insulin-sensitive tissues, and whether this represents a broader principle of endocannabinoid system regulation.