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ECS is Physiology

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Endocannabinoid Science Education
Endocannabinoid Science Education

ECS is Physiology

Tag: Endocannabinoids

Critical analysis Divided illustration contrasting mainstream omega-6 fatty acid research on left with neglected endocannabinoid system CB1 CB2 receptor pathways anandamide 2-AG hidden behind broken wall on right alongside cannabis leaf and ignored research files

The Missing System: How a Major 2026 Review on Cardiometabolic Health Ignores the Endocannabinoid System

Posted on February 2, 2026February 2, 2026 By Stefan Broselid

Last August, I wrote about a troubling pattern in inflammation research: brilliant scientists studying arachidonic acid metabolism while remaining “blissfully unaware that half the arachidonic acid story exists in a parallel research universe.” I documented how eicosanoid researchers and endocannabinoid scientists study the same substrate, same concentration ranges, same tissues—yet publish in…

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Critical analysis Silhouette of a person running on a treadmill with a glowing ribbon of blood or plasma flowing behind them, shifting from red dots on the left to organized teal and gold particles on the right, illustrating how the body transforms exercise stress into ordered molecular signals.

ECS and Exercise: The Invisible Architecture of Fitness

Posted on December 10, 2025 By Stefan Broselid

The body keeps secrets in its blood. On a Tuesday morning in late 2024, 491 men and women stepped onto treadmills and cycle ergometers across several research institutions. None of them knew they were about to reveal something profound about the mechanics of human fitness. They simply pushed themselves toward…

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Endocannabinoid System (ECS) Soybean oil and linoleic acid tipping gut lipid balance: diagram showing linoleic acid driving arachidonic acid toward eicosanoids while endocannabinoids decrease, with a bottle of soybean oil and soybeans.

Soybean oil, linoleic acid, and the gut ECS

Posted on September 19, 2025September 19, 2025 By Stefan Broselid

A recent study titled ‘Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice‘ shows that eating a lot of linoleic acid from soybean oil changes lipid chemistry in the gut in a way that weakens the protective endocannabinoid system and strengthens inflammatory…

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Endocannabinoid System (ECS) Chemical structure of Agmatine overlaid on a micrograph, with text: The Agmatine-ECS Connection - New Hope for ASD by Boosting 2-AG and Calming the Brain.

The Agmatine-ECS-ASD Connection: New Hope for ASD by Boosting 2-AG and Calming the Brain

Posted on May 22, 2025May 22, 2025 By Stefan Broselid

Explore groundbreaking research on agmatine’s connection to the endocannabinoid system (ECS) in Autism (ASD). Discover how it may boost 2-AG, calm brain inflammation, and offer new hope for understanding and potentially supporting ASD.

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