A new review argues that higher linoleic acid exposure may be beneficial. But dietary intake, circulating LA and tissue fatty-acid composition are not the same biological exposure. This article explains why that distinction matters for arachidonic acid, membrane biology and the endocannabinoid system.
Tag: Endocannabinoidome
Commentary
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The Endocannabinoid System Is No Longer the Limiting Factor? Almost.
A new review argues that policy and stigma, rather than lack of ECS science, are now the main barriers to cannabinoid medicine. I agree, but an important gap remains: medicine still lacks a practical clinical physiology of the endocannabinoid system.
Endocannabinoid System (ECS)
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Bariatric Surgery Progressively Recouples the eCBome
How Bariatric Surgery Recouples the Endocannabinoidome For years, obesity has been framed as a simple problem of “too many calories in, not enough out.” The endocannabinoidome (eCBome) tells a different story. In severe obesity, the lipid‑signaling network that should help regulate appetite, energy balance and metabolic health is present, but…
Endocannabinoid System (ECS)
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Beyond the ECS: Why you absolutely need a balanced diet
Your body produces its own cannabis-like molecules. Right now, as you read this, your cells are manufacturing compounds that interact with the same receptors that THC targets. But here’s what most people don’t realize: this system extends far beyond what we traditionally call the “endocannabinoid system”, and the food on…
Scientific Summary
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A Paradigm-Shift in Endocannabinoidome Pharmacology – Adenylyl Cyclases as Lipid-Sensing Receptors
Introduction: A New Role for Dietary Fats For decades, fats have been categorized as either “good” or “bad,” depending on their effects on cholesterol or calorie counts. However, groundbreaking research by Landau etal. (2024) reveals that fats are far more than energy sources—they act as cellular signalsthat directly influence how our cells function. The study shows that adenylyl cyclases (ACs)—enzymes traditionally…
Educational video
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Understanding the Endocannabinoidome: A Deep Dive into Human Physiology
We’re excited to share Dr. Stefan Broselid’s comprehensive lecture on the endocannabinoidome (eCBome), presented earlier this year. This detailed presentation explores how this complex physiological system influences human health and disease. Key Topics Covered: The lecture particularly emphasizes: This presentation is especially valuable for: For a deeper understanding, we recommend…
Scientific Summary
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The Hidden Link: Maternal Diet, Endocannabinoidome, and Infant Health
Discover the profound impact of maternal diet on infant health through the endocannabinoidome. Recent research reveals how the balance of omega-6 and omega-3 fatty acids during pregnancy shapes fetal brain development, potentially influencing long-term metabolic health and eating behaviors. Learn why current dietary guidelines may need reevaluation and what this means for expectant mothers.