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Endocannabinoid Science Education
Endocannabinoid Science Education

ECS is Physiology

Tag: ECS

Endocannabinoid System (ECS) Soybean oil and linoleic acid tipping gut lipid balance: diagram showing linoleic acid driving arachidonic acid toward eicosanoids while endocannabinoids decrease, with a bottle of soybean oil and soybeans.

Soybean oil, linoleic acid, and the gut ECS

Posted on September 19, 2025September 19, 2025 By Stefan Broselid

A recent study titled ‘Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice‘ shows that eating a lot of linoleic acid from soybean oil changes lipid chemistry in the gut in a way that weakens the protective endocannabinoid system and strengthens inflammatory…

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Commentary llustration showing rows of scientists in lab coats and blindfolds standing in a tunnel filled with laboratory equipment, mathematical formulas, and the words “fatty acids” and “anti-inflammatory” written on the walls. Light shines at the end of the tunnel, symbolizing limited vision or awareness. On the right, the text reads “How inflammation research ignores the endocannabinoid system (ECS): When scientific tunnel vision becomes institutional blindness.” The ECS.education logo appears at the bottom right.

How Scientific Tunnel Vision in Inflammation Research Ignores the Endocannabinoid System (ECS)

Posted on August 19, 2025 By Stefan Broselid

When scientific tunnel vision becomes institutional blindness Lessons from history’s scientific blind spots Science has a troubling habit of missing the forest for the trees. For decades, gastroenterologists dismissed the idea that bacteria could cause stomach ulcers—until Barry Marshall proved Helicobacter pylori was the culprit by infecting himself. Geologists ridiculed…

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Endocannabinoid System (ECS) Infographic slide breaking down the Endocannabinoid System (ECS) as a dietary precursor-driven symbiotic homeostatic suprasystem, with sequential symbols: a fork and knife for 'dietary' (fueled by food nutrients), a building block for 'precursor-driven' (built from fatty acids), reciprocal arrows with gut microbes for 'symbiotic' (mutual interaction with microbiome), a yin-yang for 'homeostatic' (maintains internal balance), and a network diagram for 'suprasystem' (integrates multiple organ systems)

The Endocannabinoid System: Dietary Precursor-Driven ECS & Medical Education Gap

Posted on July 23, 2025 By Stefan Broselid

The Misunderstood Master Regulator The endocannabinoid system (ECS) is often considered the “cannabis system,” but this label ignores its true—and far broader and more important—role in holistic health. Instead of being defined by external substances, the ECS is a dietary precursor-driven, symbiotic, homeostatic suprasystem: a dynamic physiological network that maintains body-wide…

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Endocannabinoid System (ECS) Illustration of an overweight person sitting next to a stylized neuron and molecular structures, visually representing the concept that obesity rewires the endocannabinoid system.

Obesity Rewires Your Endocannabinoid System (ECS): How Fat, Liver, Heart & Brain Are Transformed

Posted on June 17, 2025 By Stefan Broselid

Obesity is more than excess fat—it’s a disorder of endocannabinoid system (ECS) dysfunction. Explore how obesity rewires CB1 signaling in fat, liver, heart, and brain, driving chronic disease.

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Endocannabinoid System (ECS) Paracetamol as an Analgesic DAGL Inhibitor – Mechanism Confirmed by Jesus et al. 2025 Preprint

Paracetamol Confirmed as a Direct Analgesic DAGL Inhibitor: New Preprint Evidence

Posted on June 4, 2025June 4, 2025 By Stefan Broselid

Important Note: This blog post discusses findings from a recent scientific preprint, meaning the research has not yet been formally peer-reviewed. Preprints allow for rapid dissemination of findings, but results should be interpreted cautiously until confirmed by peer-reviewed publication. Recently, we reported on a surprising new way that paracetamol (also known…

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Critical analysis

Omega-6, Mortality, and Your ECS: Unpacking the Latest UK Biobank Bombshell

Posted on April 27, 2025 By Stefan Broselid

A major UK Biobank study found higher plasma linoleic acid (LA) linked to lower mortality, seemingly contradicting concerns about high dietary omega-6 driving ECS dysfunction. This post unpacks the findings, distinguishing between plasma snapshots and tissue arachidonic acid (AA) realities, and explains why the omega-6/omega-3 balance and ECS perspective remain crucial for understanding metabolic health.

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The Missing Link in Medicine: How the Endocannabinoid System (ECS) could Revolutionize Healthcare

Posted on February 1, 2025February 1, 2025 By Stefan Broselid

Why isn’t the endocannabinoid system (ECS) taught in medical schools? This ancient system regulates hunger, pain, metabolism, and immunity—and it’s under attack from processed foods and outdated education. Learn how omega-6 fats disrupt the ECS, drive chronic disease, and what we can do to fix healthcare. Share this video to…

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Educational video

Understanding Medical Cannabis and the ECS

Posted on December 13, 2024December 13, 2024 By Stefan Broselid

The endocannabinoid system (ECS) is one of the most important physiological systems in our body, regulating processes like mood, sleep, and pain. Yet, many healthcare professionals know little about it. This disconnect becomes even more striking when paired with the high but till growing acceptance of medical cannabis as a…

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Scientific Summary

The Great Medical Education Blind Spot: How 2,470 ECS Publications Go Ignored

Posted on November 24, 2024November 24, 2024 By Stefan Broselid

A critical analysis of four influential publications reveals a troubling disconnect in medical education: while thousands of researchers document the Endocannabinoid System’s crucial role in homeostatic regulation, mainstream medical education continues to operate in isolation from this knowledge. This systematic exclusion creates dangerous knowledge gaps in healthcare delivery.

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Scientific Summary

The Medical Cannabis Paradox: High Acceptance, Low Understanding Among Healthcare Professionals

Posted on November 5, 2024 By Stefan Broselid

A striking paradox emerges from recent research: while 80% of healthcare professionals accept medical cannabis as legitimate therapy, less than 1% understand the endocannabinoid system through which it works. This disconnect highlights a critical gap in medical education.

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