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ECS is Physiology

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Endocannabinoid Science Education
Endocannabinoid Science Education

ECS is Physiology

Tag: ECS.education

Commentary Header graphic for an ECS.education article titled ‘When Percentages Lie: Rethinking Omega‑6 Risk Biomarkers’. Two simple scatter‑plot cartoons show linoleic‑acid–related cardiometabolic risk: on the left, risk plotted against LA in µmol/L with a bold red arrow sloping up; on the right, risk plotted against LA as percent of total fatty acids with a bold green arrow sloping down, illustrating how concentration and percentage give opposite trends. On the far right, a clear plastic bottle pours golden cooking oil next to a linoleic acid structural formula and the ECS.education logo, with the study DOI printed near the top.

When Percentages Lie: Rethinking Omega‑6 (LA & AA) Risk Biomarkers and Endocannabinoid Substrates

Posted on December 4, 2025December 4, 2025 By Stefan Broselid

The blind spot in fatty acid epidemiology Since the 1960s, most circulating fatty acid data have been reported as “percent of total” rather than as absolute concentrations, because gas chromatography methods naturally produce compositional peak areas that are easy to turn into percentages (Sergeant et al., 2016; Lagerstedt et al.,…

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Endocannabinoid System (ECS) Satirical cartoon depicting a biochemical plateau where molecules cluster in a safety zone while warning signs point to an arachidonic acid canyon and inflammation zone below—illustrating the hidden dangers of excess linoleic acid in modern diets.

The Biochemical Plateau: Rethinking Linoleic Acid and Heart Health

Posted on October 23, 2025 By Stefan Broselid

The Linoleic Acid Paradox: Protection or Peril? For decades, linoleic acid has enjoyed a privileged place in nutritional policy. It is the cornerstone of “heart-healthy” messaging, the molecular mascot of seed oils, and the quiet passenger in countless processed foods. But beneath this reputation lies a paradox: the very molecule…

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Commentary Split-screen comparison of enzyme inhibitor effects: Day 1 shows dramatic metabolic improvements (53% insulin drop, 23% reduced food intake) when DAGL and NAPE-PLD are blocked, but Day 7 reveals complete failure as arachidonic acid substrate reroutes to inflammatory COX/LOX pathways, causing weight rebound, inflammation, and glucose dysfunction

The Enzyme Inhibitor Paradox: Why Anti-Obesity Drugs Keep Failing

Posted on October 19, 2025October 19, 2025 By Stefan Broselid

A new study just proved something remarkable: researchers found a way to slash insulin levels by 53% in just two hours. Food intake dropped 23%. Body weight fell within 24 hours. The pharmaceutical industry should be celebrating. Except there’s a problem. By day seven, it stopped working. Completely. The mice…

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Announcements Illustration announcing “Peer‑review passed” for a publication in the journal “I JCMCS: International Journal of Clinical & Medical Case Studies,” with a facing page reading “Bridging the gap: Integrating the endocannabinoid system into medical education” beside cartoon figures of a lab‑coated clinician holding a clipboard and a person at a laptop, green molecular icons and a cannabis leaf in the background, and a footer line stating “The ECS.education community has a milestone to celebrate.”

From Preprint to Peer Review: ECS.education Paper Accepted in IJCMCS

Posted on August 29, 2025August 29, 2025 By Stefan Broselid

The ECS.education community has a milestone to celebrate: our manuscript, “Bridging the gap: Integrating the endocannabinoid system into medical education,” has passed independent, double‑blind peer review and is now published in the International Journal of Clinical & Medical Case Studies (IJCMCS). Built around three cornerstone ECS.education analyses, the paper consolidates…

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Endocannabinoid System (ECS) Illustration of an overweight person sitting next to a stylized neuron and molecular structures, visually representing the concept that obesity rewires the endocannabinoid system.

Obesity Rewires Your Endocannabinoid System (ECS): How Fat, Liver, Heart & Brain Are Transformed

Posted on June 17, 2025 By Stefan Broselid

Obesity is more than excess fat—it’s a disorder of endocannabinoid system (ECS) dysfunction. Explore how obesity rewires CB1 signaling in fat, liver, heart, and brain, driving chronic disease.

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Scientific Summary

Dietary Omega-3/6 Balance: New Research Links Fatty Acid Ratios to Chronic Disease and Longevity

Posted on March 12, 2025March 12, 2025 By Stefan Broselid

New research reveals countries with high omega-3 consumption enjoy 2.63 extra years of healthy life expectancy compared to nations with typical Western diets. Groundbreaking clinical evidence shows omega-6 fatty acids increase inflammatory markers while omega-3s counteract these effects. Your starting omega-3/6 baseline significantly impacts how your body responds to dietary interventions, offering new insights for personalized nutrition approaches.

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The Missing Link in Medicine: How the Endocannabinoid System (ECS) could Revolutionize Healthcare

Posted on February 1, 2025February 1, 2025 By Stefan Broselid

Why isn’t the endocannabinoid system (ECS) taught in medical schools? This ancient system regulates hunger, pain, metabolism, and immunity—and it’s under attack from processed foods and outdated education. Learn how omega-6 fats disrupt the ECS, drive chronic disease, and what we can do to fix healthcare. Share this video to…

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Commentary

Challenging the Daily Mail: The Science Behind Medical Cannabis for ADHD and Menopause

Posted on January 27, 2025January 27, 2025 By Stefan Broselid

Professor Sir Robin Murray’s claim that ‘cannabis has the same effect as drinking a pint’ for psychological conditions, published in the Daily Mail, oversimplifies the science behind medical cannabis. This commentary explores the evidence supporting cannabis as a therapeutic option for ADHD and menopause while addressing misconceptions about its efficacy and safety.

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Educational video

Understanding Medical Cannabis and the ECS

Posted on December 13, 2024December 13, 2024 By Stefan Broselid

The endocannabinoid system (ECS) is one of the most important physiological systems in our body, regulating processes like mood, sleep, and pain. Yet, many healthcare professionals know little about it. This disconnect becomes even more striking when paired with the high but till growing acceptance of medical cannabis as a…

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Critical analysis Illustration showing integration points of ECS knowledge into medical curricula, featuring a medical educator presenting a flowchart of physiological systems and their connections to the Endocannabinoid System.

Beyond Omission: Integrating ECS into Medical Education – A Blueprint for Change

Posted on November 26, 2024November 26, 2024 By Stefan Broselid

Executive Summary An analysis of the Physiological Society’s 2020 “Physiological Objectives for Medical Students” curriculum guide reveals a critical gap: the complete omission of the Endocannabinoid System (ECS). This official curriculum guidance document, which establishes core physiological knowledge for new doctors, overlooks a system fundamental to maintaining homeostasis across multiple…

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